GENE_ASSOCIATION: ( PFI1020c ) PROTEIN_CLASS: 1.1.1.205 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 2E-122 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( MAL13P1.324 ) PROTEIN_CLASS: 1.1.1.21 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( MAL13P1.324 ) PROTEIN_CLASS: 1.1.1.21 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( MAL13P1.324 ) PROTEIN_CLASS: 1.1.1.21 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False BRENDA_HIT: FRENDA OTHER_NOTES: Weak evidence, unused reaction in final network. GENE_ASSOCIATION: ( MAL13P1.324 ) PROTEIN_CLASS: 1.1.1.21 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False BRENDA_HIT: FRENDA OTHER_NOTES: Weak evidence, unused reaction in final network. GENE_ASSOCIATION: ( PF13_0141 and PF13_0144 ) PROTEIN_CLASS: 1.1.1.27 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 4E-101 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0137 ) PROTEIN_CLASS: 1.1.1.271 SUBSYSTEM: 00051 SHARKHUNT_EVALUE: 3.1E-59 PRESENT_IN_PLASMODB: False OTHER_NOTES: GDP-L-fucose represents glycolsylation in the biomass function GENE_ASSOCIATION: ( PFF0895w ) PROTEIN_CLASS: 1.1.1.37 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 1.4E-76 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFF0895w ) PROTEIN_CLASS: 1.1.1.37 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 1.4E-76 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF13_0242 ) PROTEIN_CLASS: 1.1.1.42 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 2E-103 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0520 ) PROTEIN_CLASS: 1.1.1.44 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 1E-178 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0511 ) PROTEIN_CLASS: 1.1.1.49 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 6E-141 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF11_0157 and PFC0275w and PFL0780w ) PROTEIN_CLASS: 1.1.1.8 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 1E-109 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( MAL3P2.24 ) PROTEIN_CLASS: 1.1.5.3 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Included in MPMP but nowhere else, same core compounds as R842 PROTEIN_CLASS: 1.11.1.6 SUBSYSTEM: 00630 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PFL0595c ) PROTEIN_CLASS: 1.11.1.9 SUBSYSTEM: 00480 SHARKHUNT_EVALUE: 9.5E-47 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFE0555w ) PROTEIN_CLASS: 1.14.19.1 SUBSYSTEM: 01040 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA OTHER_NOTES: Simplified reaction, mechanism is complex, multi-gene and multi-reaction. Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF08_0071 and PFF1130c ) PROTEIN_CLASS: 1.15.1.1 SUBSYSTEM: 00480 SHARKHUNT_EVALUE: 3E-74 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF10_0154 and PF14_0053 and PF14_0352 ) PROTEIN_CLASS: 1.17.4.1 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF10_0154 and PF14_0053 and PF14_0352 ) PROTEIN_CLASS: 1.17.4.1 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF10_0154 and PF14_0053 and PF14_0352 ) PROTEIN_CLASS: 1.17.4.1 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0154 and PF14_0053 and PF14_0352 ) PROTEIN_CLASS: 1.17.4.1 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0154 and PF14_0053 and PF14_0352 ) PROTEIN_CLASS: 1.17.4.1 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0598 ) PROTEIN_CLASS: 1.2.1.12 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 1E-171 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF11_0256 and PF14_0441 ) PROTEIN_CLASS: 1.2.4.1 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 6E-110 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF11_0256 and PF14_0441 ) PROTEIN_CLASS: 1.2.4.1 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 6E-110 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF08_0045 and PF13_0070 and PFC0170c ) PROTEIN_CLASS: 1.2.4.2 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF08_0045 and PF13_0070 and PFC0170c ) PROTEIN_CLASS: 1.2.4.2 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFF0160c ) PROTEIN_CLASS: 1.3.3.1 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 2E-88 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0334 and PFL0630w ) PROTEIN_CLASS: 1.3.99.1 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF14_0334 ) PROTEIN_CLASS: 1.4.1.14 SUBSYSTEM: 00251 SHARKHUNT_EVALUE: 0.03 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF08_0132 ) PROTEIN_CLASS: 1.4.1.2 SUBSYSTEM: 00910 SHARKHUNT_EVALUE: 2E-37 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA PROTEIN_CLASS: 1.4.4.2 SUBSYSTEM: 00260 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( MAL13P1.284 ) PROTEIN_CLASS: 1.5.1.2 SUBSYSTEM: 00330 SHARKHUNT_EVALUE: 4.8E-71 PRESENT_IN_PLASMODB: True OTHER_NOTES: Reaction flux zeroed to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( MAL13P1.284 ) PROTEIN_CLASS: 1.5.1.2 SUBSYSTEM: 00330 SHARKHUNT_EVALUE: 4.8E-71 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PFD0830w ) PROTEIN_CLASS: 1.5.1.3 SUBSYSTEM: 00790 SHARKHUNT_EVALUE: 7.8E-40 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: small section of folate biosynthesis used in nucleotide synthesis only GENE_ASSOCIATION: ( PFB0880w ) PROTEIN_CLASS: 1.5.1.7 SUBSYSTEM: 00300 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF14_0508 ) PROTEIN_CLASS: 1.6.1.1 SUBSYSTEM: 00760 SHARKHUNT_EVALUE: 0.04 PRESENT_IN_PLASMODB: False BRENDA_HIT: FRENDA OTHER_NOTES: representative of R00115 and R00094 pair. GENE_ASSOCIATION: ( PF13_0353 and PFI1140w ) PROTEIN_CLASS: 1.6.2.2 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Part of a simplified pathway, paired to SFAE. Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PFI1140w ) PROTEIN_CLASS: 1.6.2.4 SHARKHUNT_EVALUE: 3.2E-96 PRESENT_IN_PLASMODB: True BRENDA_HIT: no OTHER_NOTES: Manually balanced from unbalanced equivalent in KEGG, linked to SFAE. Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF08_0066 and PFL1550w ) PROTEIN_CLASS: 1.8.1.4 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 2E-129 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF08_0066 and PFL1550w ) PROTEIN_CLASS: 1.8.1.4 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 2E-129 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF08_0066 and PFL1550w ) PROTEIN_CLASS: 1.8.1.4 SUBSYSTEM: 00260 SHARKHUNT_EVALUE: 2E-129 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0192 ) PROTEIN_CLASS: 1.8.1.7 SHARKHUNT_EVALUE: 4E-175 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: No associated KEGG pathway. Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0192 ) PROTEIN_CLASS: 1.8.1.7 SUBSYSTEM: 00480 SHARKHUNT_EVALUE: 4E-175 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PFI1170c ) PROTEIN_CLASS: 1.8.1.9 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0.036 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFD0830w ) PROTEIN_CLASS: 2.1.1.45 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 6E-61 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0534 and PFL1720w ) PROTEIN_CLASS: 2.1.2.1 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 9E-146 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( MAL13P1.390 and PF13_0345 and PF14_0497 ) PROTEIN_CLASS: 2.1.2.10 SUBSYSTEM: 00260 SHARKHUNT_EVALUE: 1.1E-64 PRESENT_IN_PLASMODB: True OTHER_NOTES: Reaction flux zeroed to prevent thermodynamically unacceptable cycle. PROTEIN_CLASS: 2.1.2.8 SUBSYSTEM: 00300 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False GENE_ASSOCIATION: ( MAL13P1.221 ) PROTEIN_CLASS: 2.1.3.2 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 3.9E-89 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PFF0530w ) PROTEIN_CLASS: 2.2.1.1 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFF0530w ) PROTEIN_CLASS: 2.2.1.1 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE PROTEIN_CLASS: 2.2.1.2 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 0.000006 PRESENT_IN_PLASMODB: False BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( PF10_0407 and PFC0170c ) PROTEIN_CLASS: 2.3.1.12 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 1.1E-22 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF13_0120 and PF13_0121 ) PROTEIN_CLASS: 2.3.1.61 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 1E-131 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PFB0505c and PFF1275c and PFI1125c ) PROTEIN_CLASS: 2.3.1.85 SUBSYSTEM: 00061 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Simplified reaction, mechanism is complex, multi-gene and multi-reaction, multiple KEGG pathways, 00061 chosen GENE_ASSOCIATION: ( PF10_0218 and PFF0455w ) PROTEIN_CLASS: 2.3.3.1 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 6.8E-96 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PFE0660c ) PROTEIN_CLASS: 2.4.2.1 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFE0660c ) PROTEIN_CLASS: 2.4.2.1 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFE0630c ) PROTEIN_CLASS: 2.4.2.10 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 5.5E-32 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0121 ) PROTEIN_CLASS: 2.4.2.8 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 2.6E-41 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0121 ) PROTEIN_CLASS: 2.4.2.8 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 2.6E-41 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0121 ) PROTEIN_CLASS: 2.4.2.8 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 2.6E-41 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PFB0200c ) PROTEIN_CLASS: 2.6.1.1 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 2.4E-88 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFF0435w ) PROTEIN_CLASS: 2.6.1.13 SUBSYSTEM: 00330 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFF1155w ) PROTEIN_CLASS: 2.7.1.1 SUBSYSTEM: 00051 SHARKHUNT_EVALUE: 3E-145 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFF1155w ) PROTEIN_CLASS: 2.7.1.1 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 3E-145 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFF1155w ) PROTEIN_CLASS: 2.7.1.1 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 3E-145 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF07_0072 and PF11_0294 and PFI0755c ) PROTEIN_CLASS: 2.7.1.11 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0269 ) PROTEIN_CLASS: 2.7.1.30 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 1E-163 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( PF10_0363 and PFF1300w ) PROTEIN_CLASS: 2.7.1.40 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Located to apicoplast in BRENDA, included in both compartments GENE_ASSOCIATION: ( PF10_0363 and PFF1300w ) PROTEIN_CLASS: 2.7.1.40 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Located to apicoplast in BRENDA, included in both compartments GENE_ASSOCIATION: ( MAL13P1.40 and PFI1105w ) PROTEIN_CLASS: 2.7.2.3 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 2E-164 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFA0555c ) PROTEIN_CLASS: 2.7.4.14 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0.001 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF08_0062 and PF10_0086 and PFA0530c and PFD0755c ) PROTEIN_CLASS: 2.7.4.3 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 3.4E-28 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF13_0349 and PFF0275c ) PROTEIN_CLASS: 2.7.4.6 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 4.2E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFI1420w ) PROTEIN_CLASS: 2.7.4.8 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 1.5E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFL2465c ) PROTEIN_CLASS: 2.7.4.9 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 1.4E-48 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFL2465c ) PROTEIN_CLASS: 2.7.4.9 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 1.4E-48 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF13_0143 and PF13_0157 ) PROTEIN_CLASS: 2.7.6.1 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 1E-112 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0774 and PFL0675c ) PROTEIN_CLASS: 2.7.7.13 SUBSYSTEM: 00051 SHARKHUNT_EVALUE: 1E-101 PRESENT_IN_PLASMODB: False OTHER_NOTES: GDP-Mannose included in Biomass function as consituent of Mannan, chosen as carbohydrate store from similarity to Leishmania major, Chavali et al. GENE_ASSOCIATION: ( PF14_0511 ) PROTEIN_CLASS: 3.1.1.31 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 1.5E-24 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFD0311w and PFL0285w ) PROTEIN_CLASS: 3.1.2.6 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 1.8E-75 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFL0305c ) PROTEIN_CLASS: 3.1.3.5 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( MAL13P1.118 and MAL13P1.119 and PF14_0672 and PFL0475w ) PROTEIN_CLASS: 3.1.4.17 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 6.6E-60 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( MAL13P1.118 and MAL13P1.119 and PF14_0672 and PFL0475w ) PROTEIN_CLASS: 3.1.4.17 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 6.6E-60 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( MAL3P3.14 ) PROTEIN_CLASS: 3.5.1.2 SUBSYSTEM: 00910 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA OTHER_NOTES: Gene via reaction with same EC number in KEGG only. Reaction flux zeroed to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0697 ) PROTEIN_CLASS: 3.5.2.3 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 1.9E-45 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFI0320w ) PROTEIN_CLASS: 3.5.3.1 SUBSYSTEM: 00330 SHARKHUNT_EVALUE: 2.6E-69 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( PF13_0259 ) PROTEIN_CLASS: 3.5.4.13 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF10_0289 ) PROTEIN_CLASS: 3.5.4.4 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 5.7E-58 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( MAL13P1.146 ) PROTEIN_CLASS: 3.5.4.6 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 1E-174 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( PFC0710w ) PROTEIN_CLASS: 3.6.1.1 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF11_0282 ) PROTEIN_CLASS: 3.6.1.23 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 3.2E-19 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0297 ) PROTEIN_CLASS: 3.6.1.5 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 7.3E-54 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA OTHER_NOTES: Evidence from SharkHunt and KEGG only. Flux direction limited to prevent thermodynamically unacceptable cycle. PROTEIN_CLASS: 3.6.1.8 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0654 and PFL0950c ) PROTEIN_CLASS: 3.6.3.1 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PFD0285c and PFD0670c ) PROTEIN_CLASS: 4.1.1.18 SUBSYSTEM: 00300 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF10_0225 ) PROTEIN_CLASS: 4.1.1.23 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0.000000000000028 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0246 ) PROTEIN_CLASS: 4.1.1.31 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF13_0234 ) PROTEIN_CLASS: 4.1.1.49 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0425 ) PROTEIN_CLASS: 4.1.2.13 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 2E-131 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0210 ) PROTEIN_CLASS: 4.1.2.4 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 2.7E-36 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF11_0410 ) PROTEIN_CLASS: 4.2.1.1 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 0.00000000038 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF10_0155 ) PROTEIN_CLASS: 4.2.1.11 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFI1340w ) PROTEIN_CLASS: 4.2.1.2 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF13_0229 ) PROTEIN_CLASS: 4.2.1.3 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF13_0229 ) PROTEIN_CLASS: 4.2.1.3 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF08_0077 ) PROTEIN_CLASS: 4.2.1.47 SUBSYSTEM: 00051 SHARKHUNT_EVALUE: 5E-142 PRESENT_IN_PLASMODB: False GENE_ASSOCIATION: PROTEIN_CLASS: 4.2.1.58 PRESENT_IN_PLASMODB: False OTHER_NOTES: Evidence of fatty Acid Elongation in Mi-ichi et al. Mechanism unknown so simplified reaction provided, KEGG Pathway not exact but links to FA metabolism PROTEIN_CLASS: 4.2.3.3 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 0.000011 PRESENT_IN_PLASMODB: False OTHER_NOTES: Doubtful. Only evidence is in MPMP, sharkhunt hit too large to be considered relevant, required for synthesis of D-lactate (Pfaller et al.) D-lactate is not a required product. GENE_ASSOCIATION: ( PFB0295w ) PROTEIN_CLASS: 4.3.2.2 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 9E-74 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF11_0145 and PFF0230c ) PROTEIN_CLASS: 4.4.1.5 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 1.6E-40 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0788 and PFB0420w ) PROTEIN_CLASS: 4.6.1.1 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 4.7E-19 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( MAL13P1.301 and PF11_0395 ) PROTEIN_CLASS: 4.6.1.2 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 7.4E-49 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA OTHER_NOTES: Direct evidence in BRENDA via alternative EC number of same Reaction ID GENE_ASSOCIATION: ( PFL0960w ) PROTEIN_CLASS: 5.1.3.1 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 3.4E-63 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF14_0378 and PFC0831w ) PROTEIN_CLASS: 5.3.1.1 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 2.9E-93 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFE0730c ) PROTEIN_CLASS: 5.3.1.6 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 1.5E-63 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( MAL8P1.156 ) PROTEIN_CLASS: 5.3.1.8 SUBSYSTEM: 00051 SHARKHUNT_EVALUE: 1.6E-17 PRESENT_IN_PLASMODB: False GENE_ASSOCIATION: ( PF14_0341 ) PROTEIN_CLASS: 5.3.1.9 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 1.7E-76 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0341 ) PROTEIN_CLASS: 5.3.1.9 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 1.7E-76 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF14_0341 ) PROTEIN_CLASS: 5.3.1.9 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 1.7E-76 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF11_0208 and PFD0660w ) PROTEIN_CLASS: 5.4.2.1 SUBSYSTEM: 00010 SHARKHUNT_EVALUE: 5E-113 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PF10_0122 ) PROTEIN_CLASS: 5.4.2.2 SUBSYSTEM: 00030 SHARKHUNT_EVALUE: 0.0000075 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( PF10_0169 ) PROTEIN_CLASS: 5.4.2.8 SUBSYSTEM: 00051 SHARKHUNT_EVALUE: 3.1E-79 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PF10_0334 and PF11_0097 ) PROTEIN_CLASS: 6.2.1.4 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 8E-135 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA OTHER_NOTES: Reaction flux zeroed to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0295 ) PROTEIN_CLASS: 6.2.1.5 SUBSYSTEM: 00020 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True GENE_ASSOCIATION: ( PFI1110w ) PROTEIN_CLASS: 6.3.1.2 SUBSYSTEM: 00910 SHARKHUNT_EVALUE: 2.6E-68 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PFI0925w ) PROTEIN_CLASS: 6.3.2.2 SUBSYSTEM: 00251 SHARKHUNT_EVALUE: 1E-142 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA GENE_ASSOCIATION: ( PFE0605c ) PROTEIN_CLASS: 6.3.2.3 SUBSYSTEM: 00480 SHARKHUNT_EVALUE: 3.9E-56 PRESENT_IN_PLASMODB: False BRENDA_HIT: BRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0573 and PF14_0664 ) PROTEIN_CLASS: 6.3.4.14 SUBSYSTEM: 00061 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA GENE_ASSOCIATION: ( PF13_0044 ) PROTEIN_CLASS: 6.3.4.16 SUBSYSTEM: 00910 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: FRENDA OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF14_0100 ) PROTEIN_CLASS: 6.3.4.2 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF13_0287 ) PROTEIN_CLASS: 6.3.4.4 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 6.1E-36 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PF10_0123 ) PROTEIN_CLASS: 6.3.5.2 SUBSYSTEM: 00230 SHARKHUNT_EVALUE: 6.6E-67 PRESENT_IN_PLASMODB: True BRENDA_HIT: DIRECT EVIDENCE GENE_ASSOCIATION: ( PFC0395w ) PROTEIN_CLASS: 6.3.5.4 SUBSYSTEM: 00252 SHARKHUNT_EVALUE: 1E-114 PRESENT_IN_PLASMODB: True OTHER_NOTES: Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF13_0044 ) PROTEIN_CLASS: 6.3.5.5 SUBSYSTEM: 00240 SHARKHUNT_EVALUE: 0.0000019 PRESENT_IN_PLASMODB: True BRENDA_HIT: BRENDA OTHER_NOTES: Manually balanced from unbalanced equivalent in KEGG. Flux direction limited to prevent thermodynamically unacceptable cycle. GENE_ASSOCIATION: ( PF10_0409 and PF14_0664 ) PROTEIN_CLASS: 6.4.1.2 SUBSYSTEM: 00061 SHARKHUNT_EVALUE: 8E-157 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: BRENDA Direct evidence is for EC number not Reaction ID (EC reaction link defined outside of KEGG ontology), Manually balanced from unbalanced equivalent in KEGG GENE_ASSOCIATION: ( PF10_0409 and PF14_0664 ) PROTEIN_CLASS: 6.4.1.2 SUBSYSTEM: 00620 SHARKHUNT_EVALUE: 8E-157 PRESENT_IN_PLASMODB: False BRENDA_HIT: DIRECT EVIDENCE OTHER_NOTES: BRENDA Direct evidence is for EC number not Reaction ID (EC reaction link defined outside of KEGG ontology), Manually balanced from unbalanced equivalent in KEGG. Flux direction limited to prevent thermodynamically unacceptable cycle. PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux set to additional R-lactate efflux suggested by Vander Jagt 1990 based on my measured effluxes PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux set to measured efflux PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux forced to rate suggested by Atamna 1997 PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Efflux only PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux limited to measured rates PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux limited to efflux rate from Olszewski et al. 2010 PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux limited to make hypoxanthine uptake the primary purine source PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Flux limited to make hypoxanthine uptake the primary purine source PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to maximum possible value without being measured PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to measured value PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to stop free arginine to proline conversion PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to stop free arginine to proline conversion PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to stop aspartate as primary carbon source or sink. High flux does not affect growth rate but is not consistent with measurements PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to measured uptake (half of measured glucose) PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: flux limited to measured uptake (half of measured glucose) GENE_ASSOCIATION: PROTEIN_CLASS: unknown SUBSYSTEM: PRESENT_IN_PLASMODB: False OTHER_NOTES: flux set to reproduce measured growth rate. Magnitude similar to Leishmania Major model. PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Biomass must be produced PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SUBSYSTEM: 00330 SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: No evidence for existence PROTEIN_CLASS: unknown SUBSYSTEM: SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False OTHER_NOTES: Simplified reaction, mechanism is complex, multi-gene and multi-reaction PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown SHARKHUNT_EVALUE: 0 PRESENT_IN_PLASMODB: False PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: H2O2 can only move out of the vacuole which contains ingested catalase PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Influx only PROTEIN_CLASS: unknown PRESENT_IN_PLASMODB: False OTHER_NOTES: Oxyhaemoglobin can only be digested